Successful cryopreservation of Wuchereria bancrofti microfilariae

Lectin-binding characteristics of Wuchereria bancrofti microfilariae.

The binding of 10 different lectins to the surface of microfilariae of Wuchereria bancrofti has been investigated. Wheat germ agglutinin (WGA) and Helix pomatia lectin (HPA) bound specifically to the sheathed microfilariae indicating the presence of N-acetyl-D-glucosamine and N-acetyl-D-galactosamine respectively on the surface. Exsheathed microfilariae did not react with any of the lectins. Tr...

Transmission of Wuchereria Bancrofti

me about the mode of transmission of Wuchereria bancrojti. I understood that it was through the bite of an infected mosquito (Culex) larva passing through the bite puncture though capable of penetrating the healthy skin. I have just read in the ' Science and Practice of, Surgery', 1948 ed. (vol. I, p. 258) by Romanis and Mitchiner, that the infection is through drinking water in which the bodie...

Wuchereria bancrofti: detection of microfilariae in asymptomatic microfilaremic individuals with Setaria digitata antigens.

A dot-ELISA for detection of microfilariae of Wuchereria bancrofti in an endemic area was developed. This test can differentiate the endemic normals from the microfilaraemic asymptomatic individuals. Antigens of molecular weight 130 and 52 kDa of the cattle filaria worm Setaria digitata were used for this test. It was observed that these two antigens were also present in the serum of asymptomat...

An unusual presentation of Wuchereria bancrofti infection.

Prevalence of Wuchereria bancrofti in Georgetown, Guyana1

A random sample bloodsmear survey was conducted during evening hours in Georgetown, Guyana, to determine the prevalence of Wuchereria bancrofti microfilariae. In all, 182 of 2,818 persons tested (6.5%) yielded positive results-indicating that the overall prevalence of Bancroffian filariasis has not diminished and may be on the rise. Relatively high prevalences found in children and adolescents ...